GOSSIPOL EFFECT ON MICE (Mus domesticus domesticus) BLOOD

Authors

  • Reginaldo Nassar Ferreira UFG
  • Liliane Araújo Mendes de Almeida UFG
  • Rejane Costa Ferreira CNPq

DOI:

https://doi.org/10.5216/pat.v25i1.2736

Keywords:

Gossipol, mice, blood

Abstract

Twenty thirty day-old male mice weighing 25 g were divided in two groups: Group 1: oral saline solution (control), and Group 2: oral gossipol acetic-acid at 20 mg/kg. Forty days after treatments and leukocytes were counted through Newbawer counting chamber. Leukometry showed 9,241 leukocytes/mm3 for the control and 6,125 leukocytes/mm3 for the gossipol treated group (significant difference for P=0.05). Erythrometry showed 6,596,000 erythrocytes/mm3 and 6,399,000 erythrocytes/mm3 for control and gossipol treated mice, respectively. It was concluded that gossipol may induce a deleterious effect on the organism defense cells.

KEY-WORDS: Gossipol; mice; blood.

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Published

2007-12-12

Issue

v. 25, n. 1, Jan./Jun. 1995

Section

Research Article

License

Authors will not be paid for published articles and must waive their copyright in favor of the PAT journal. On the other hand, they are solely responsible for the content of those articles, even if the Editor holds the right to adjust them to the norms of the journal. Authors are allowed to publish their articles simultaneously in their institutional repositories, as soon as the original publication at the PAT journal is mentioned.

How to Cite

FERREIRA, R. N.; ALMEIDA, L. A. M. DE; FERREIRA, R. C. GOSSIPOL EFFECT ON MICE (Mus domesticus domesticus) BLOOD. Pesquisa Agropecuária Tropical [Agricultural Research in the Tropics], v. 25, n. 1, p. 63–68, 12 Dec.2007.