Análise de fatores de risco, alterações clínicas e marcadores laboratoriais em vacas com diferentes tipos de deslocamento de abomaso
Resumo
A depender do antímero em que ocorre a paratopia abomasal o deslocamento de abomaso (DA) pode ser classificado em diferentes tipos que influenciam diretamente as alterações clínico-laboratoriais. O objetivo deste estudo foi analisar os principais fatores de risco, manifestações clínicas e alterações laboratoriais (perfil energético, hormonal, mineral e enzimático) de vacas com diferentes tipos de DA. Foram utilizadas 104 vacas atendidas na Clínica de Bovinos de Garanhuns, Campus da Universidade Federal Rural de Pernambuco, diagnosticadas com DA, sendo 67 casos de DA a esquerda (G2), 25 de DA a direita (G3) e 12 de vólvulo abomasal (G4). O grupo controle (G1) foi composto por 19 vacas clinicamente saudáveis. Os dados quantitativos foram testados pelos testes de ANOVA ou Kruskal-Wallis, enquanto as variáveis categóricas foram submetidas ao teste exato de Fisher. Foi realizado um estudo de correlação entre variáveis quantitativas dentro dos grupos e todas as análises consideraram p<0,05. Dentre os fatores de risco identificados destacam-se o sistema intensificado de criação (96,15 %), a raça (holandesa [50,0 %]), e número de partos (≤ 2 partos [49,04 %]). Dentre os achados clínicos, a desidratação, taquicardia, timpania ruminal e distensão abdominal foram mais frequentes nos animais do G3 e G4. A análise do perfil energético demonstrou elevação nos níveis de AGNEs, glicose e cortisol dos animais com DA em comparação com as vacas do grupo controle. Hipocalcemia e hipocalemia foram constatados nos animais com DA, e a hiperlactatemia foi mais acentuada no G4. A intervenção clínica-cirúrgica foi realizada em 86,54 % dos animais, com um desfecho positivo em 76,92 % dos casos, sem diferença quanto ao tipo de DA. Diante dos resultados, é possível constatar a influência do tipo de DA na intensidade das alterações clínico-laboratoriais, com maiores implicações no vólvulo abomasal, sendo os fatores predisponentes para sua ocorrência identificáveis e passíveis de métodos de controle e prevenção adequados.
Palavras-chave: abomaso deslocado; metabolismo energético; vólvulo abomasal; perfil mineral.
Downloads
Referências
Câmara ACL, Afonso JAB, Costa NA, Mendonça CL, Souza MI, Borges JRJ. Fatores de risco, achados clínicos, laboratoriais e avaliação terapêutica em 36 bovinos com deslocamento de abomaso. Pesq. Vet. Bras. 2010;30(5):453464. https://doi.org/10.1590/S0100-736X2010000500014
Constable PD, Hinchcliff KW, Done SH, Grunberg W. Diseases of the alimentary tract-Ruminant. In: Constable PD, Hinchcliff KW, Done SH, Grunberg W. Veterinary Medicine: A Textbook of the Diseases of Cattle, Horses, Sheep, Pigs, and Goats. 11th ed. St. Louis, Missouri: Elsevier; 2017. p. 436-621.
Mezzetti M, Cattaneo L, Passamonti MM, Lopreiato V, Minuti A, Trevisi E. The transition period updated: a review of the new insights into the adaptation of dairy cows to the new lactation. Dairy. 2021;2(4):617-636. https://doi.org/10.3390/ dairy2040048
Soares GSL, Costa NA, Afonso JAB, Souza MI, Cajueiro JFP, Silva JCR, Ferreira F, Mendonça CL. Digestive diseases of cattle diagnosed at the “Clínica de Bovinos de Garanhuns”-UFRPE: retrospective study and influence of seasonality. Pesq. Vet. Bras. 2021;41:e06800. https://doi.org/10.1590/1678-5150-pvb-6800
Dirksen G. Die Erweiterung, Verlagerung und Drehung des Labmagens beim Rind. Zentralbl. Veterinärmed. 1961;8:977-1015. https://doi.org/10.1111/j.1439-0442.1961.tb00677.x
Constable PD, St Jean G, Hull BL, Rings DM, Hoffsis GF. Preoperative prognostic indicators in cattle with abomasal volvulus. J. Am. Vet. Med. Assoc. 1991a;198:2077-2085.
Constable PD, St Jean G, Hull BL, Rings DM, Hoffsis GF. Prognostic value of surgical and postoperative findings in cattle with abomasal volvulus. J. Am. Vet. Med. Assoc. 1991b;199:892-898.
Meylan M. Prognostic indicators in cattle with right-sided displacement of the abomasum and abomasal volvulus. Schweiz. Arch. Tierheilkd. 1999;141:413-418.
Smith DF. Right-side torsion of the abomasum in dairy cows: classification of severity and evaluation of outcome. J. Am. Vet. Med. Assoc. 1978;173:108-111.
Geishauser T. Abomasal displacement in the bovine: a review on character, occurrence, aetiology and pathogenesis. J. Vet. Med. A. 1995;42:229-251. https://doi.org/10.1111/j.1439-0442.1995.tb00375.x
Kuiper R. Abomasal diseases. Bovine Pract. 1991;26:111-117. https://doi.org/10.21423/bovine-vol1991no26p111-117
Breukink HJ, Kuiper R. Digestive disorders following obstruction of flow of ingesta through the abomasum and small intestine. Bovine Pract. 1980;15:139-143. https://doi.org/10.21423/bovine-vol1980no15p139-143
Braun U, Nuss K, Reif S, Hilbe M, Gerspach C. Left and right displaced abomasum and abomasal volvulus: comparison of clinical, laboratory and ultrasonographic findings in 1982 dairy cows. Acta Vet. Scand. 2022;64:40. https://doi.org/10.1186/s13028-022-00656-9
Patelli THC, Fagnani R, da Cunha Filho LFC, Souza FA, Wolf GS, Cardoso MJ, Seiva FRF, Matsuda J. Hypocalcemia in displacement of the abomasum in cattle: study of 39 cases. Pesq. Vet. Bras. 2017;37:17-22. https://doi.org/10.1590/ s0100-736x2017000100003
Coşkun A, Aydoğdu U, Guzelbektes H. Metabolic profile in dairy cattle with displacement of the abomasum. Turk. Vet. J. 2022;4:18-23. https://doi.org/10.51755/turkvetj.1172715
Leblanc SJ, Leslie KE, Duffield TF. Metabolic predictors of displaced abomasum in dairy cattle. J. Dairy Sci. 2005;88:159-170. https://doi.org/10.3168/jds.S0022-0302(05)72674-6
Ribeiro ACS, Soares GSL, Coutinho LT, Cajueiro JFP, Souto RJC, Silva BHS, Soares PC, Mendonça CL, Afonso JAB. Cardiac, energy and hormonal blood markers, and lactatemia in cows with displaced abomasum. Acta Sci. Vet. 2020;48:e103310. http://dx.doi.org/10.22456/1679-9216.103310
Stengärde L, Holtenius K, Tråven M, Hultgren J, Niskanen R, Emanuelson U. Blood profiles in dairy cows with displaced abomasum. J. Dairy Sci. 2010;93:4691-4699. https://doi.org/10.3168/jds.2010-3295
Dirksen G. Sistema Digestivo. In: Dirksen G, Grunder HD, Stober M. Rosenberger. Exame Clínico dos Bovinos. 3ª ed. Guanabara Koogan, Rio de Janeiro; 1993. p. 163-224.
Harvey JW. Hematology procedures. In: Harvey JW (Ed). Veterinary hematology. A diagnostic guide and color atlas. 1st ed. St. Louis, Missouri: Elsevier, 2012. p. 11-32.
Djoković R, Dosković V, Cincović M, Belić B, Fratrić N, Jašović B, Lalović M. Estimation of insulin resistance in healthy and ketotic cows during an intravenous glucose tolerance test. Pak. Vet. J. 2017;37:387-392.
Holtenius P, Holtenius K. A model to estimate insulin sensitivity in dairy cows. Acta Vet. Scand. 2007;49:29. https:// doi.org/10.1186/1751-0147-49-29
Petrie A, Watson P, editors. Statistics for veterinary and animal science. 3rd ed. Wiley-Blackwell, Chichester; 2013. p. 396.
Dohoo IR. Dealing with deficient and missing data. Prev. Vet. Med. 2015;122:221-228. http://dx.doi.org/10.1016/j. prevetmed.2015.04.006
Van Buuren S, Groothuis-Oudshoorn K. MICE: Multivariate imputation by chained equations in R. J. Stat. Softw. 2011;45:1-67. https://doi.org/10.18637/jss.v045.i03
R Core Team. R: A Language and Environment for Statistical Computing. R Foundation for Statistical Computing, Vienna, Austria, 2024. https://www.R-project.org/
Doll K, Sickinger M, Seeger T. New aspects in the pathogenesis of abomasal displacement. Vet. J. 2009;181:90-96. https://doi.org/10.1016/j.tvjl.2008.01.013
Constable PD, Miller GY, Hoffsis GF, Hull BL, Rings DM. Risk factors for abomasal volvulus and left abomasal displacement in cattle. Am. J. Vet. Res. 1992;53:1184-1192. https://doi.org/10.2460/ajvr.1992.53.7.1184
Rohn M, Tenhagen BA, Hofmann W. Survival of dairy cows after surgery to correct abomasal displacement: 1. Clinical and laboratory parameters and overall survival. J. Vet. Med. A. 2004;51:294-299. https://doi.org/10.1111/j.14390442.2004.00649.x
Cameron REB, Dyk PB, Herdt TH, Kaneene JB, Miller R, Bucholtz HF, Liesman JS, Vandehaar MJ, Emery RS. Dry cow diet, management, and energy balance as risk factors for displaced abomasum in high producing dairy herds. J. Dairy Sci. 1998;81:132-139. https://doi.org/10.3168/jds.S0022-0302(98)75560-2
Shaver RD. Nutritional risk factors in the etiology of left displaced abomasum in dairy cows: a review. J. Dairy Sci. 1997;80:2449-2453. https://doi.org/10.3168/jds.S0022-0302(97)76197-6
Stengärde LU, Pehrson BG. Effects of management, feeding, and treatment on clinical and biochemical variables in cattle with displaced abomasum. Am. J. Vet. Res. 2002;63:137-142. https://doi.org/10.2460/ajvr.2002.63.137
Svendsen P. Etiology and pathogenesis of abomasal displacement in cattle. Nord. Vet. Med. 1969;21(Suppl. 1):1-60.
Krey S. Keimgehalt und Gasbildungsvermögen des Labmageninhaltes gesunder Kühe und von solchen mit Labmagenverlagerung. Dissertação, Faculty of Veterinary Medicine, Giessen, 2025. http://dx.doi.org/10.22029/ jlupub-12108
Proios I, Grünberg W. Preoperative and surgical predictors of the treatment outcome of dairy cows with right abomasal displacement: a retrospective study of 234 cases. Animals. 2023;13:2887. https://doi.org/10.3390/ani13182887
Wolf V, Hamann H, Scholz H, Distl O. Einflüsse auf das Auftreten von Labmagenverlagerungen bei deutschen Holsteinkühen. Dtsch. Tierärztl. Wochenschr. 2001a;108:403-408.
Wolf V, Hamann H, Scholz H, Distl O. Systematische Einflüsse auf das Auftreten von Labmagenverlagerungen bei Deutschen Holsteinkühen. Züchtungskunde. 2001b;73:257-265.
Jubb TF, Malmo J, Davis GM, Vawser AS. Left-side displacement of the abomasum in dairy cows at pasture. Aust. Vet. J. 1991;68:140-142. https://doi.org/10.1111/j.1751-0813.1991.tb03157.x
Dyck HR, Perotta JH, Rodrigues TC, Galvão JA, Brum JS, Barros Filho IR. Occurrence of abomasal displacement in dairy cows from high-yielding dairy farms of Paraná State, Southern Brazil. Semina: Ciênc. Agrar. 2023;44:9-18. https:// doi.org/10.5433/1679-0359.2023v44n1p9
Freick M, Sieber I, Endtmann A, Passarge U, Passarge O. Endoskopische Labmagenreposition am stehenden Tier in einem sächsischen Milchviehbetrieb. Tierärztl. Umsch. 2013;68:311-321.
Sexton MF, Buckley W, Ryan E. A study of 54 cases of left displacement of the abomasum: February to July 2005. Ir. Vet. J. 2007;60:605-609. https://doi.org/10.1186/2046-0481-60-10-605
Hansen LB. Consequences of selection for milk yield from a geneticist's viewpoint. J. Dairy Sci. 2000;83:1145-1150. https://doi.org/10.3168/jds.S0022-0302(00)74980-0
Van Winden SCL, Jorritsma R, Müller KE, Noordhuizen JPTM. Feed intake, milk yield, and metabolic parameters prior to left displaced abomasum in dairy cows. J. Dairy Sci. 2003;86:1465-1471. https://doi.org/10.3168/jds.s00220302(03)73730-8
Van Winden SCL, Jorritsma R, Müller KE, Noordhuizen JPTM. Feed intake, milk yield, and metabolic parameters prior to left displaced abomasum in dairy cows. J. Dairy Sci. 2003;86:1465-1471. https://doi.org/10.3168/jds.s00220302(03)73730-8
Buczinski S, Boulay G, Francoz D. Preoperative and postoperative L-lactatemia assessment for the prognosis of right abomasal disorders in dairy cattle. J. Vet. Intern. Med. 2015;29:375-380. https://doi.org/10.1111/jvim.12490
Fubini SL, Gröhn YT, Smith DF. Right displacement of the abomasum and abomasal volvulus in dairy cows: 458 cases (1980–1987). J. Am. Vet. Med. Assoc. 1991;198:460-464
Soares GSL, Afonso JAB, Coutinho LT, Souto RJC, Silva NAA, Conceição AI, Silva JCR, Mendonça CLD. Clinical and laboratory indicators predictive of the negative outcome of gastrointestinal emergencies in cattle. Cienc. Anim. Bras. 2023;24:e74401. https://doi.org/10.1590/1809-6891v24e-74401P
Leek BF. Clinical diseases of the rumen: a physiologist's view. Vet. Rec. 1983;113:10-14. https://doi.org/10.1136/ vr.113.1.10
Mueller K. Diagnosis, treatment and control of left displaced abomasum in cattle. In Pract. 2011;33:470-481. https:// doi.org/10.1136/inp.d6079
Kerby M. Differential diagnosis and management of right-sided abdominal ‘ping’ in dairy cattle. In Pract. 2008;30:98104. https://doi.org/10.1136/inpract.30.2.98
Smith DF. Abomasal volvulus. Bovine Pract. 1987;22:162-164. https://doi.org/10.21423/bovine-vol0no22p162-164
Munch SL, Nielsen SS, Krogh MA, Capion N. Prevalence of abomasal lesions in Danish Holstein cows at the time of slaughter. J. Dairy Sci. 2019;102:5403-5409. https://doi.org/10.3168/jds.2018-15757
Nielsen SS, Krogh MA, Munch SL, Capion N. Effect of non-perforating abomasal lesions on reproductive performance, milk yield and carcass weight at slaughter in Danish Holstein cows. Prev. Vet. Med. 2019;167:101-107. https://doi. org/10.1016/j.prevetmed.2019.04.001
Zadnik T. A comparative study of the hemato-biochemical parameters between clinically healthy cows and cows with displacement of the abomasum. Acta Vet. 2003;53:297-310. https://doi.org/10.2298/AVB0306297Z
Aslan N, Yiğitarslan K, Büyükoğlu T. Investigation of lipid mobilization and oxidative stress parameters in the serum before and after surgery of cows with left displacement abomasum. Int. J. Vet. Anim. Res. 2022;5:80-88. https://doi. org/10.5281/zenodo.7020512
Kaneco JJ, Harvey JW, Bruss ML. Clinical biochemistry of domestic animals. 5th ed. Sand Diego: Academic Press, 1997. 932p.
Kerestes M, Faigl V, Kulcsár M, Balogh O, Földi J, Fébel H, Huszenicza G. Periparturient insulin secretion and whole-body insulin responsiveness in dairy cows showing various forms of ketone pattern with or without puerperal metritis. Domest. Anim. Endocrinol. 2009;37(4):250-261. https://doi.org/10.1016/j.domaniend.2009.07.003
Hayirli A. The role of exogenous insulin in the complex of hepatic lipidosis and ketosis associated with insulin resistance phenomenon in postpartum dairy cattle. Vet. Res. Commun. 2006;30:749-774. https://doi.org/10.1007/ s11259-006-3320-6
Landa L. Pain in domestic animals and how to assess it: a review. Vet. Med. 2012;57:185-192. http://dx.doi. org/10.17221/5915-VETMED
Muylle E, Van Den Hende C, Sustronck B, Deprez P. Biochemical profiles in cows with abomasal displacement estimated by blood and liver parameters. J. Vet. Med. A. 1990;37:259-263. https://doi.org/10.1111/j.1439-0442.1990. tb00903.x
Van Meirhaeghe H, Deprez P, Van Den Hende C, Muylle E. Plasma glucose clearance and insulin response in cows with abomasal displacement. J. Vet. Med. A. 1988a;35:221-228. https://doi.org/10.1111/j.1439-0442.1988.tb00026.x
Van Meirhaeghe H, Deprez P, Van Den Hende C, Muylle E. The influence of insulin on abomasal emptying in cattle. J. Vet. Med. A. 1988b;35:213-220. https://doi.org/10.1111/j.1439-0442.1988.tb00025.x
Daniel RC. Motility of the rumen and abomasum during hypocalcaemia. Can. J. Comp. Med. 1983;47:276-280.
Murray RD, Horsfield JE, McCormick WD, Williams HJ, Ward D. Historical and current perspectives on the treatment, control and pathogenesis of milk fever in dairy cattle. Vet. Rec. 2008;163:561-565. https://doi.org/10.1136/vr.163.19.561
Ott D, Schrapers KT, Aschenbach JR. Changes in the relationship between ionized and total calcium in clinically healthy dairy cows in the period around calving. Animals. 2021;11:1036. https://doi.org/10.3390/ani11041036
Constable PD, Grünberg W, Staufenbiel R, Stämpfli HR. Clinicopathologic variables associated with hypokalemia in lactating dairy cows with abomasal displacement or volvulus. J. Am. Vet. Med. Assoc. 2013;242:826-835. https://doi. org/10.2460/javma.242.6.826
Sattler N, Fecteau G. Hypokalemia syndrome in cattle. Vet. Clin. Food Anim. Pract. 2014;30:351-357. https://doi. org/10.1016/j.cvfa.2014.04.004
Komatsu Y, Itoh N, Taniyama H, Kitazawa T, Yokota H, Koiwa M, Ohtsuka H, Terasaki N, Maeno K, Mizoguchi M, Takeuchi Y, Tanigawa M, Nakamura T, Watanabe H, Matsuguchi Y, Kukino T, Honma A. Classification of abomasal displacement in cows according to histopathology of the liver and clinical chemistry. J. Vet. Med. A. 2002;49:482-486. https://doi.org/10.1046/j.1439-0442.2002.00484.
Itoh N, Koiwa M, Hatsugaya A, Yokota H, Taniyama H, Okada H, Kudo K. Comparative analysis of blood chemical values in primary ketosis and abomasal displacement in cows. J. Vet. Med. A. 1998;45:293-298. https://doi.org/10.1111/j.1439-0442.1998.tb00830.x
Allen SE, Holm JL. Lactate: physiology and clinical utility. J. Vet. Emerg. Crit. Care. 2008;18:123-132. https://doi.org/10.1111/j.1476-4431.2008.00286.x
Radcliffe RM, Buchanan BR, Cook VL, Divers TJ. The clinical value of whole blood point-of-care biomarkers in large animal emergency and critical care medicine. J. Vet. Emerg. Crit. Care. 2015;25:138-151. https://doi.org/10.1111/vec.12276
Downloads
Publicado
Edição
Seção
Licença
Direitos autorais (c) 2026 Ciência Animal Brasileira / Brazilian Animal Science

Este trabalho está licenciado sob uma licença Creative Commons Attribution 4.0 International License.
Autores que publicam nesta revista concordam com os seguintes termos:
- Autores mantém os direitos autorais e concedem à revista o direito de primeira publicação, com o trabalho simultaneamente licenciado sob a Licença Creative Commons Attribution que permite o compartilhamento do trabalho com reconhecimento da autoria e publicação inicial nesta revista.
- Autores têm autorização para assumir contratos adicionais separadamente, para distribuição não-exclusiva da versão do trabalho publicada nesta revista (ex.: publicar em repositório institucional ou como capítulo de livro), com reconhecimento de autoria e publicação inicial nesta revista.
- Autores têm permissão e são estimulados a publicar e distribuir seu trabalho online (ex.: em repositórios institucionais ou na sua página pessoal) a qualquer ponto antes ou durante o processo editorial, já que isso pode gerar alterações produtivas, bem como aumentar o impacto e a citação do trabalho publicado (Veja O Efeito do Acesso Livre).
Como Citar
Declaração de dados
-
Os dados de pesquisa estão contidos no próprio manuscrito





















