Avaliação de estresse oxidativo no plasma de bovinos leiteiros com mastite

Cecilia Gabriela Rubert Possenti; Roberta Cattaneo Horn; Natacha Cossettin Mori; Vanderlei Ribas Junior; Diego Pascoal Golle; Jana Koefender

doi:10.1590/1809-6891v19e-39754

EVALUATION OF OXIDATIVE STRESS IN PLASMA OF DAIRY COWS WITH MASTITIS

Authors

Cecilia Gabriela Rubert Possenti Universidade de Cruz Alta, Cruz Alta, Rio Grande do Sul, Brasil
Roberta Cattaneo Horn Universidade de Cruz Alta, Cruz Alta, Rio Grande do Sul, Brasil https://orcid.org/0000-0001-9258-8005 (unauthenticated)
Natacha Cossettin Mori Universidade de Cruz Alta, Cruz Alta, Rio Grande do Sul, Brasil
Vanderlei Ribas Junior Universidade de Cruz Alta, Cruz Alta, Rio Grande do Sul, Brasil
Diego Pascoal Golle Universidade de Cruz Alta, Cruz Alta, Rio Grande do Sul, Brasil https://orcid.org/0000-0002-5264-8007 (unauthenticated)
Jana Koefender Universidade de Cruz Alta, Cruz Alta, Rio Grande do Sul, Brasil https://orcid.org/0000-0002-5882-9669 (unauthenticated)

DOI:

https://doi.org/10.1590/1809-6891v19e-39754

Abstract

Bovine mastitis is associated with an endogenous antibacterial response mediated by the production of reactive species. However, excess oxidative reactions can trigger cellular apoptosis, aggravating the clinical state of the animals. In this context, the objective of this study was to evaluate the plasma redox response of dairy cows with and without mastitis submitted or not to antibiotic therapy. The cows were divided into control group (G1), cows without mastitis; group G2, cows with mastitis without antimicrobial treatment; group G3, cows with mastitis treated with antibiotics. Blood samples were collected after the first milking of the morning. The existence of lipoperoxidation (LPO) and the levels of carbonylated proteins (CPs), reduced glutathione (GSH), ascorbic acid (ASA), and uric acid (UA) were analyzed. The G3 animals showed increase in LPO and CPs. In all groups GSH levels were unchanged. Plasma ASA and AU values were decreased in the G2 and G3 groups. The results demonstrated that antimicrobial treatment seems to aggravate the oxidative damages present in bovine mastitis, reinforcing the importance of the search for therapeutic alternatives in order to minimize this effect.
Keywords: antibiotics; cellular oxidation; cows.

Downloads

Download data is not yet available.

Downloads

Published

2018-04-25

Issue

Vol. 19 (2018): Continuous publication

Section

VETERINARY MEDICINE

License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Authors who publish with this journal agree to the following terms:

Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
Authors are permitted and encouraged to post their work online (e.g. in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).

How to Cite

POSSENTI, C. G. R. et al. EVALUATION OF OXIDATIVE STRESS IN PLASMA OF DAIRY COWS WITH MASTITIS. Brazilian Animal Science/ Ciência Animal Brasileira, v. 19, p. 1–9, 25 Apr.2018.